GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| BLCA | cis | rs12908161 | 1 | rs34570071 | chr15:85280212 | LOC388152 | chr15:84867600-84898920:- | -0.24 | -4.17 | 3.84E-5 | Schizophrenia |
| BLCA | cis | rs2243480 | 1 | rs34577383 | chr7:65385726 | CCT6P1 | chr7:65216092-65228661:+ | 0.31 | 4.38 | 1.53E-5 | Diabetic kidney disease |
| BLCA | cis | rs1577917 | 1 | rs34581302 | chr6:86705948 | SNHG5 | chr6:86386726-86388451:- | -0.52 | -9.2 | 2.39E-18 | Response to antipsychotic treatment |
| BLCA | cis | rs1577917 | 1 | rs34622557 | chr6:86630852 | SNHG5 | chr6:86386726-86388451:- | -0.51 | -9.04 | 7.68E-18 | Response to antipsychotic treatment |
| BLCA | cis | rs2243480 | 1 | rs34637256 | chr7:65360131 | CCT6P1 | chr7:65216092-65228661:+ | 0.32 | 4.47 | 1.03E-5 | Diabetic kidney disease |
| BLCA | cis | rs2243480 | 1 | rs34702770 | chr7:65344823 | CCT6P1 | chr7:65216092-65228661:+ | 0.32 | 4.47 | 1.03E-5 | Diabetic kidney disease |
| BLCA | cis | rs2243480 | 1 | rs34703416 | chr7:65300642 | CCT6P1 | chr7:65216092-65228661:+ | 0.32 | 4.48 | 1.0E-5 | Diabetic kidney disease |
| BLCA | cis | rs4808801 | 1 | rs34746918 | chr19:18539744 | LRRC25 | chr19:18501955-18508421:- | -0.1 | -3.84 | 0.000142 | Breast cancer |
| BLCA | cis | rs950169 | 1 | rs34751999 | chr15:84758419 | LOC388152 | chr15:84867600-84898920:- | -0.26 | -4.61 | 5.56E-6 | Schizophrenia |
| BLCA | cis | rs9475752 | 1 | rs34812189 | chr6:56806727 | BEND6 | chr6:56819773-56892138:+ | -0.28 | -3.87 | 0.00013 | Menarche (age at onset) |
| BLCA | cis | rs2243480 | 1 | rs34815098 | chr7:65292254 | CCT6P1 | chr7:65216092-65228661:+ | 0.31 | 4.39 | 1.49E-5 | Diabetic kidney disease |
| BLCA | cis | rs17108533 | 1 | rs34817530 | chr14:71228462 | MAP3K9 | chr14:71194856-71275888:- | 0.4 | 4.18 | 3.65E-5 | Response to antipsychotic treatment in schizophrenia (reasoning) |
| BLCA | cis | rs17030613 | 1 | rs34848593 | chr1:113240106 | ST7L | chr1:113066142-113162405:- | 0.44 | 6.49 | 2.68E-10 | Diastolic blood pressure;Blood pressure |
| BLCA | cis | rs1577917 | 1 | rs34852683 | chr6:86702330 | SNHG5 | chr6:86386726-86388451:- | -0.5 | -8.76 | 6.51E-17 | Response to antipsychotic treatment |
| BLCA | cis | rs10508921 | 1 | rs34895954 | chr10:52007016 | FAM21A | chr10:51827684-51893268:+ | -0.53 | -4.62 | 5.34E-6 | Thiazide-induced adverse metabolic effects in hypertensive patients |